This book addresses new problems and challenges of development in the 21st century, trying to answer questions, how to turn nations that are underdeveloped and torn apart by conflict into good places to live and how to help them develop. Issues connected with globalization, political challenges, constitutional systems as a condition for development are addressed. Problems of entrepreneurship in developing regions, as well as transnational connections between countries, making them vulnerable to economic crises are also touched upon. Finally, issues connected with institutional design, clean energy, health service challenges, as well as gender issues are analyzed. All those issues refer to developing countries in Asia, Africa, Latin America, as well as Central and Eastern Europe.